The Essence of PET Scans in Determining and Healing Lymphoma

The malignant cells that cause lymphoma begin at the lymph nodes. Tumor develops when there is an enlargement of the node. The case is quite similar to lymphoid leukemia, but this only involves the bone marrow where the blood cells are produced through the haematopoesis process as well as the circulating blood.

The first description of this dreaded disease was first published in 1832. This was done by Thomas Hodgkin, thus the name of the Hodgkin type of this illness. There are many other forms that have been discovered since then and all these are now part of a large group of illnesses that are known as hematological neoplasms.

When you start feeling that you have the symptoms, especially the enlarged lymph nodes, you should seek the help of your doctor. This case may not always mean that you are sick, but to make sure that you are okay, you have to get yourself checked by a professional. The first step that doctors may require you to undergo is biopsy, the type of which will be dictated as to the organs that are infected with the disease. After it was established that you already have it, the doctors will then try to categorize from which type of this illness you are suffering from. Before you can be given proper treatment for your condition, your bone marrow needs to be tested and you have to go through various tests and scans.

PET Scans

One of the special kinds of scans that you may be asked to undergo is PET scan or Positron Emission Tomography. This is able to determine the cancers based on the high activity that is happening on the cancer cell.

Other types of scans provide different results. For example, MR type and CT scans present good quality photographs of the various body parts where you can view the masses of tumors and swollen nodes. The problem with these scans is the fact that doctors cannot based their findings whether a person has the illness based on the size and shape of what was photographed through these processes. This is what PET scans are able to fill in the blanks.

PET scans are useful in the procedure because these are used to map out the disease on a person’s body. Along with the other kinds of tests, all results can be used to determine the stages of the disease. This is also able to find out if the lump that showed up on other tests, is cancerous or not. After the condition was settled, the doctor can then proceed to give the necessary treatment, whether you need to go through chemotherapy or it will be best to undergo radiation.

After some cycles of chemotherapy, you have to go through the same scans and it will help to assess how well your body is responding to it. When the treatment has been done, you still have to go through PET scans to know whether the lump still has cancer cells, scar tissue or it has already been healed.

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Lymphoma, the cancer of the lymph system, is one of the hardest diseases to deal with. This is because up until now, no cure has been discovered to appease the fear of people at risk in this type of disease. Although there are some preventive measures that are advertised to prevent cancer cells from growing, nothing can stop it fully once it has multiplied and disabled the function of specific organs in the body.

Lymph system refers to a network of interconnected nodes and thin tubes which paves the way for the white blood cells to be carried out in the different parts of the body. White blood cells are very important since these helps fight infections. When these cells are struck by cancer cells, it will affect the way the white blood cells and will lead to its dysfunction.

Lymphoma targets a part of the lymph system and it does not refer to single cancer but to a group of many cancers that are related. As of today, there are about 30 types of lymphoma including “Mantle Cell Lymphoma,” “Malt Lymphoma,” “Cutaneous (Skin) Lymphoma,” “Diffuse Large B-Cell Lymphoma,” “Burkitt Lymphoma,” and “Primary CNS Lymphoma” among others but these types can belong to two different categories including the Hodgkin Disease and Non-Hodgkin Lymphoma.

According to experts, both categories may exhibit the same symptoms that are why the diagnosis and sets of examinations are done. But, the major difference in these two types will be noticeable depending on the person being affected.

Red flags of lymphoma

Lymphoma could be considered as a silent threat because it will take some time before its symptoms occur. And, when they do, they can be so common or “generic” thats why many people dont take it so seriously. Unless the symptoms become so noticeable and appear ever so often, that’s the only time when the person suffering from it would consider consulting a doctor.

If you are at risk, say belong to a family whose history include cancerspecifically cancer of the lymph systemthen it would be best to undergo a check up once you:

– feel painless lumps in the neck, armpits or groin. Experts say that this is the most commonand at timesthe ONLY one that is the symptom of lymphoma. Once you have enlarged nodes, it is the best time to undergo a check up. You can check if your nodes are enlarged when changing clothes or while taking a bath. You can also ask your sister or your partner to check it for you if you feel uncertain about the lumps. However, not all emerged lymph nodes are always signs of lymphoma so its better if you consult a physician to be sure.

– drastic weight loss. Once cancer cells attack the lymph system, the person will suddenly lose weight without apparent reason. In fact, once lymphoma remains undetected in the coming months, the person may lose as much as 15 to 20 pounds!

Other symptoms of lymphoma aside from enlarged lymph nodes and drastic weight loss may include continuous fever, sweating excessively specially during night time despite cold weather, and severe itchiness on almost all parts of the body which are results of special chemicals that are secreted by lymphoma cells.

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These are some facts according to the Leukemia & Lymphoma Society: 19.5 out of every 100,000 people in the world develop Non-Hodgkins Lymphoma while 2.8 out of every 100,000 people in the world are diagnosed with Hodgkins disease. Hodgkins disease and Non-Hodgkins Lymphoma are two of the main classifications of lymphoma, a cancer of the bodys lymph system. The lymph system, being part of our immune system, is tasked to eliminate bacteria, diseases and infection from our body. But when the cells multiply abnormally, tumors begin to appear in the lymph nodes. You can feel these as lumps in the nodes of the neck, armpit and groin. Soon the cancer cells will spread in other parts of the body, how lymphoma spreads is a good thing to know.

Metastasis. This is a word we often hear in cancer patients. This is actually a term which refers to the spreading of cancer to the rest of the body. Lymphoma at first is a single tumor in one of the many lymph nodes of the body. What happens when the cancer cells undergo metastasis is that cancer-infected cells break away from the main tumor and moves to another part of the body. The cancer cells use the bloodstream to move from one area of the body to another. The cancer cell can attach itself to another lymph node or to other organs of the body. When it fastened firmly, the cells reproduce again until it creates another mass of tissue to form as a tumor. Then the whole process repeats itself.

For lymphoma, the cancer cells use the lymphatic system of the body to spread. The lymphatic system of the body is pretty much like the bloodstream, it is spread although out the body since it is responsible for keeping the body clean from infections and diseases. The lymphatic system is an open canal where cancer cells can travel and create more tumors.

The tumors are pretty deadly. Because of the accelerated rate of growth, these cancer cells can continue to make the tumors grow. Soon enough the tumors grow large enough that the healthy tissues or organs are prevented to function normally. Eventually the healthy tissues or organs will stop functioning which spells death to the person.

Like any cancer, lymphoma has also a number of stages. These stages describe the severity of the condition and indicate how far the cancer cells have infected the body. Stage I is the first stage of the cancer. At this level, the cancer cells have only infected one lymph node or one part of the body. Because it is still developing, this stage is also referred to as the early disease.

The second stage or Stage II is far more alarming. At this point the cancer cells have metastasis and have infected another one or even more lymph nodes or parts of the body. However, at Stage II the infection is limited to either above or below the persons diaphragm. This stage is called locally advanced disease.

Stage III is known as the advanced disease. The cancer cells at this stage have found its way on both sides of the diaphragm and have established a number of tumors in those areas. The final stage or Stage IV or widespread disease is described by spread of the cancer cells to one or more of the bodys organs such as the bone, skin, liver or lungs.

This is how lymphoma spreads. That is why it is important for an early detection of the disease for proper and effective treatment.

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Hodgkin’s lymphoma or otherwise known as Hodgkin’s disease is one of two kinds of lymphoma or a cancer of the lymphatic system. Thomas Hodgkin was the first person who published documented studies of the disease hence the cancer was named after him. Hodgkin’s lymphoma is different from the other kind of lymphoma mainly through the presence of Reed-Sternberg cells in the cancer cells. These Reed-Sternberg cells can be seen through an open biopsy. In contrast, cells seen on non-Hodgkins lymphomas are mutated B-cells or T-cells.

It has been observed that Hodgkins lymphoma oftentimes begin to develop in the lymph nodes in the neck. This is again quite different from non-Hodgkins lymphoma which beings in different locations in the body. Nonetheless, since this is cancer were talking about, from the neck lymph node spreading to other lymph node groups, the lungs, spleen, and bone marrow is only natural and inevitable if no treatment is undergone. It seems also that Hodgkin’s lymphoma targets the immediate nearby lymphatic regions before leaving eventually the lymphatic system and spreading throughout other organs of the body.

According to studies, Hodgkins lymphoma is more likely to develop in young adolescents particularly those within the age range of 15 to 24 as well as those who are more than 60 years old. Again this is quite different from non-Hodgkins lymphoma which rarely happens in young people and instead is more common to people aged 60 years old and above.

In determining a diagnosis, one can actually self-diagnose at least initially. A doctors expertise is still needed, of course, for a more accurate diagnosis of the disease. The symptoms that have been reported are not that different from the other kinds of lymphoma. The presence of a painless lump in the lymph nodes in the neck, underarm, or groin, recurrent fevers, unexplained weight loss, night sweats and itchy skins are among the warning signals of developing lymphoma.

Among the usual tests your doctors would require you to undertake includes blood tests to check abnormalities in the blood counts, blood chemistry, and abnormal erythrocyte sedimentation rate (ESR), X-rays to look at the lymph nodes, computerized tomography or CT scan and magnetic resonance imaging or MRI scans of the chest, pelvis, and abdomen to see if the cancer has already spread to other parts of the body.

Other scans that could be used to properly diagnose and determine the stage of the cancer are the positron emission tomography or PET scan which scans the cancer at a cellular level and the gallium scan which looks for radioactive intake of gallium which can mean the onset of the disease. There are other tests and procedures which doctors might conduct on you all in the aid of a proper and accurate diagnosis.

Hodgkins lymphoma has several sub-types, namely nodular sclerosis (NS) which hits the lower neck, chest and collarbone, lymphocyte predominance (LP) which is made of malignant L&H cells which have a “popcorn”, mixed cellularity (MC) which has lymph nodes that are usually contain Reed-Sternberg cells and inflammatory cells, lymphocyte depleted (LD), and nodular lymphocyte predominant (NLP).

As they say, knowing is half the battle. Knowing more about Hodgkins disease is a good thing. You can contribute fully to the decision making process if you know exactly the situation you are in.

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