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The Types of Non-Hodgkins Lymphoma

Lymphomas are cancers of the lymph system which ironically is part of the bodys defense mechanism to fight off infections and diseases. But sometimes the abnormal growth of the healthy lymphatic cells causes the tissues to mass up creating tumors and eventually becoming cancer cells. If left untreated, the cancer cells can easily break away from the tissues and begin infecting other parts of the lymphatic system and eventually moving to other organs of the body. There are essentially two kinds of lymphomas, the Hodgkins lymphoma and non-Hodgkins lymphoma.

Hodgkins lymphoma is characterized by the presence of Reed-Sternberg cells. Other lymphomas do not contain these cells so the rest of the lymphomas were classified as non-Hodgkin’s lymphoma or NHL. There are a number of sub-types of non-Hodgkin’s lymphoma. Each are quite distinct targeting specific age groups aside from having unique forms.

One kind of NHL is the lymphoblastic lymphoma or LBL which commonly occurs in children. In fact about 30% of documented cases of lymphomas in children have been classified as lymphoblastic lymphomas. LBL is very aggressive kind of NHL and has caused quite a number of deaths in the past. But because of modern medicine and treatment techniques, LBL patients have better odds of surviving the ordeal.

Unlike LBL, the diffuse histiocytic lymphoma type or DHL is a slow growing cancer. And because it is slow-growing the cancer is quite hard to detect. Also, there are times where the cancer reappears after treatment.

Another kind of NHL appears closer to the bodys surface. The cutaneous T-cell lymphoma or CTLC is a kind of lymphoma that affects the skin. What happens is that the white blood cells of the skin become cancerous. At first, the signs are dry, scaly skin with red or dark patches. These areas of the skin also itch a lot. But as the cancer cells continue to grow, the skin will develop highly noticeable tumors. Eventually the cancer cells enter the blood stream and spreads all over the body which soon infects other tissues and organs.

Although not common, the mantle cell lymphoma is another kind of non-Hodgkin’s lymphoma. This cancer borders on being rare since only an estimated 5% of people diagnosed with NHL have it. It seems that the cancer is more likely to occur in men 50 years old and older. The cancer starts off as a slow growing lymphoma but can suddenly become aggressive in later stages.

Doctors have made 4 classifications or stages of non-Hodgkin’s lymphoma which basically indicates how fast and how far the cancer cells have spread. Stage 1 is when the cancer cells are grouped in lymph node or organ of the body. In stage 2 the cancer has spread to two or more groups of lymph nodes or organs on the same side of your diaphragm. Stage 3 is where the cancer cells have infected organs on both sides of the diaphragm and finally stage 4 is when the different types of non-Hodgkins lymphoma have gone beyond the lymphatic system and infecting other organs like the liver, bones, and lungs.


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Looking Out For The Warning Signs Of Lymphoma

Lymphoma, the cancer of the lymph system, is one of the hardest diseases to deal with. This is because up until now, no cure has been discovered to appease the fear of people at risk in this type of disease. Although there are some preventive measures that are advertised to prevent cancer cells from growing, nothing can stop it fully once it has multiplied and disabled the function of specific organs in the body.

Lymph system refers to a network of interconnected nodes and thin tubes which paves the way for the white blood cells to be carried out in the different parts of the body. White blood cells are very important since these helps fight infections. When these cells are struck by cancer cells, it will affect the way the white blood cells and will lead to its dysfunction.

Lymphoma targets a part of the lymph system and it does not refer to single cancer but to a group of many cancers that are related. As of today, there are about 30 types of lymphoma including “Mantle Cell Lymphoma,” “Malt Lymphoma,” “Cutaneous (Skin) Lymphoma,” “Diffuse Large B-Cell Lymphoma,” “Burkitt Lymphoma,” and “Primary CNS Lymphoma” among others but these types can belong to two different categories including the Hodgkin Disease and Non-Hodgkin Lymphoma.

According to experts, both categories may exhibit the same symptoms that are why the diagnosis and sets of examinations are done. But, the major difference in these two types will be noticeable depending on the person being affected.

Red flags of lymphoma

Lymphoma could be considered as a silent threat because it will take some time before its symptoms occur. And, when they do, they can be so common or “generic” thats why many people dont take it so seriously. Unless the symptoms become so noticeable and appear ever so often, that’s the only time when the person suffering from it would consider consulting a doctor.

If you are at risk, say belong to a family whose history include cancerspecifically cancer of the lymph systemthen it would be best to undergo a check up once you:

– feel painless lumps in the neck, armpits or groin. Experts say that this is the most commonand at timesthe ONLY one that is the symptom of lymphoma. Once you have enlarged nodes, it is the best time to undergo a check up. You can check if your nodes are enlarged when changing clothes or while taking a bath. You can also ask your sister or your partner to check it for you if you feel uncertain about the lumps. However, not all emerged lymph nodes are always signs of lymphoma so its better if you consult a physician to be sure.

– drastic weight loss. Once cancer cells attack the lymph system, the person will suddenly lose weight without apparent reason. In fact, once lymphoma remains undetected in the coming months, the person may lose as much as 15 to 20 pounds!

Other symptoms of lymphoma aside from enlarged lymph nodes and drastic weight loss may include continuous fever, sweating excessively specially during night time despite cold weather, and severe itchiness on almost all parts of the body which are results of special chemicals that are secreted by lymphoma cells.


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Knowing Your Cancer, How Lymphoma Spreads

These are some facts according to the Leukemia & Lymphoma Society: 19.5 out of every 100,000 people in the world develop Non-Hodgkins Lymphoma while 2.8 out of every 100,000 people in the world are diagnosed with Hodgkins disease. Hodgkins disease and Non-Hodgkins Lymphoma are two of the main classifications of lymphoma, a cancer of the bodys lymph system. The lymph system, being part of our immune system, is tasked to eliminate bacteria, diseases and infection from our body. But when the cells multiply abnormally, tumors begin to appear in the lymph nodes. You can feel these as lumps in the nodes of the neck, armpit and groin. Soon the cancer cells will spread in other parts of the body, how lymphoma spreads is a good thing to know.

Metastasis. This is a word we often hear in cancer patients. This is actually a term which refers to the spreading of cancer to the rest of the body. Lymphoma at first is a single tumor in one of the many lymph nodes of the body. What happens when the cancer cells undergo metastasis is that cancer-infected cells break away from the main tumor and moves to another part of the body. The cancer cells use the bloodstream to move from one area of the body to another. The cancer cell can attach itself to another lymph node or to other organs of the body. When it fastened firmly, the cells reproduce again until it creates another mass of tissue to form as a tumor. Then the whole process repeats itself.

For lymphoma, the cancer cells use the lymphatic system of the body to spread. The lymphatic system of the body is pretty much like the bloodstream, it is spread although out the body since it is responsible for keeping the body clean from infections and diseases. The lymphatic system is an open canal where cancer cells can travel and create more tumors.

The tumors are pretty deadly. Because of the accelerated rate of growth, these cancer cells can continue to make the tumors grow. Soon enough the tumors grow large enough that the healthy tissues or organs are prevented to function normally. Eventually the healthy tissues or organs will stop functioning which spells death to the person.

Like any cancer, lymphoma has also a number of stages. These stages describe the severity of the condition and indicate how far the cancer cells have infected the body. Stage I is the first stage of the cancer. At this level, the cancer cells have only infected one lymph node or one part of the body. Because it is still developing, this stage is also referred to as the early disease.

The second stage or Stage II is far more alarming. At this point the cancer cells have metastasis and have infected another one or even more lymph nodes or parts of the body. However, at Stage II the infection is limited to either above or below the persons diaphragm. This stage is called locally advanced disease.

Stage III is known as the advanced disease. The cancer cells at this stage have found its way on both sides of the diaphragm and have established a number of tumors in those areas. The final stage or Stage IV or widespread disease is described by spread of the cancer cells to one or more of the bodys organs such as the bone, skin, liver or lungs.

This is how lymphoma spreads. That is why it is important for an early detection of the disease for proper and effective treatment.


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Common Side Effects of Lymphoma Treatments

The most commonly used treatments for lymphoma are chemotherapy and radiotherapy. Chemotherapy involves the administration or application of drugs infused into the veins of the patients. Chemotherapy could also be taken in the form of oral pills. Radiotherapy uses high-energy light rays that are specially and strategically directed at the cancer cells targeted. This form of therapy could be delivered even over small body areas (involved field radiation) or over large areas (extended field radiation).

Such lymphoma treatments are quite toxic. They are designed to strategically kill targeted cancer cells. It is not impossible that during the process, several normal cells are also being damaged. Thus, there are inevitable side effects. However, rest assured that most side effects of lymphoma treatments are only temporary. Such unlikely effects are resolved soon following completion of the treatments. Here are some of the commonly identified side effects of treatments used to cure lymphoma.

Feeling sick. There are chemotherapy drugs that could certainly make you feel nauseous or sick. There could even be several episodes of vomiting especially when chemotherapy comes with radiotherapy for the abdomen. Nausea is often prevented through administration of anti-emetics drugs prior to every cycle of chemotherapy combined with radiotherapy. These days, there are even medicines that help control nausea and vomiting.

Hair loss. Chemotherapy usually leads to excessive loss of hair. The extent of alopecia could depend on the drug used in the session. There are other effective drugs that could lead to this problem. However, there is no need to worry because hair is almost always beginning to grow back a few months after completion of the treatment. In some cases, it may take more than a year before hair growth restarts.

Falling blood count and infection. During the course of the radiotherapy or chemotherapy, your blood count could fall below optimal or normal levels. Needless to say, your white blood cells are the most affected. You know that when white cell counts dip, the body could develop several forms of infections, often accompanied by fever. Contact your doctor at once when fever appears. You might need special treatment to boost your white cell count and take care of the infection. Any drop in red blood cells could easily be remedied through blood transfusions.

Loss of appetite. Chemotherapy and radiotherapy could alter your sense of taste especially during the duration of the treatment. However, like in hair loss, the sense of taste may return to normal following completion of the lymphoma treatment. Meanwhile, you should strive to take even small meals and drink plenty of water and fluids more frequently. Remember the importance of maintaining your overall nutrition during the treatment.

Sore mouth and sore skin. Lymphoma treatments could lead to sore mouth several weeks after the start of the program. Thus, you could feel difficulty or even pain in drinking and swallowing food. In most cases, doctors recommend temporarily switching to mashed foods that are much easier to swallow. Radiotherapy could cause soreness on the skin. However, such a problem is of no concern as skin sores easily go away immediately after radiation treatment.


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