The Types of Non-Hodgkins Lymphoma
Lymphomas are cancers of the lymph system which ironically is part of the bodys defense mechanism to fight off infections and diseases. But sometimes the abnormal growth of the healthy lymphatic cells causes the tissues to mass up creating tumors and eventually becoming cancer cells. If left untreated, the cancer cells can easily break away from the tissues and begin infecting other parts of the lymphatic system and eventually moving to other organs of the body. There are essentially two kinds of lymphomas, the Hodgkins lymphoma and non-Hodgkins lymphoma.
Hodgkins lymphoma is characterized by the presence of Reed-Sternberg cells. Other lymphomas do not contain these cells so the rest of the lymphomas were classified as non-Hodgkin’s lymphoma or NHL. There are a number of sub-types of non-Hodgkin’s lymphoma. Each are quite distinct targeting specific age groups aside from having unique forms.
One kind of NHL is the lymphoblastic lymphoma or LBL which commonly occurs in children. In fact about 30% of documented cases of lymphomas in children have been classified as lymphoblastic lymphomas. LBL is very aggressive kind of NHL and has caused quite a number of deaths in the past. But because of modern medicine and treatment techniques, LBL patients have better odds of surviving the ordeal.
Unlike LBL, the diffuse histiocytic lymphoma type or DHL is a slow growing cancer. And because it is slow-growing the cancer is quite hard to detect. Also, there are times where the cancer reappears after treatment.
Another kind of NHL appears closer to the bodys surface. The cutaneous T-cell lymphoma or CTLC is a kind of lymphoma that affects the skin. What happens is that the white blood cells of the skin become cancerous. At first, the signs are dry, scaly skin with red or dark patches. These areas of the skin also itch a lot. But as the cancer cells continue to grow, the skin will develop highly noticeable tumors. Eventually the cancer cells enter the blood stream and spreads all over the body which soon infects other tissues and organs.
Although not common, the mantle cell lymphoma is another kind of non-Hodgkin’s lymphoma. This cancer borders on being rare since only an estimated 5% of people diagnosed with NHL have it. It seems that the cancer is more likely to occur in men 50 years old and older. The cancer starts off as a slow growing lymphoma but can suddenly become aggressive in later stages.
Doctors have made 4 classifications or stages of non-Hodgkin’s lymphoma which basically indicates how fast and how far the cancer cells have spread. Stage 1 is when the cancer cells are grouped in lymph node or organ of the body. In stage 2 the cancer has spread to two or more groups of lymph nodes or organs on the same side of your diaphragm. Stage 3 is where the cancer cells have infected organs on both sides of the diaphragm and finally stage 4 is when the different types of non-Hodgkins lymphoma have gone beyond the lymphatic system and infecting other organs like the liver, bones, and lungs.
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Lymphoma Warning Signs
Panicking is never a good thing. Imagine yourself running back and forth inside your house after you felt a lump of in you armpits. It is very possible that you have lymphoma or cancer of the lymph nodes. But still going around in panic is never the answer. Early detection is very important in this situation for treatment of the cancer is more effective. But one could actually check if he or she has lymphoma by looking out for a few lymphoma waning signs. But of course, self diagnosis is never a replacement for the actual, proper and effective medical testing.
As mentioned before, one of the first warning signs that you probably would observe is the presence of lumps not only in your armpits but in your neck and groin as well. These lumps are painless and signs of enlarged lymph nodes. However, an enlarged lymph node is not specific to lymphoma. There might be other underlying conditions for the cause of swollen or enlarged lymph nodes.
Another sign is sudden weight loss. If you found yourself suddenly loosing weight without no apparent cause then lymphoma might be the reason. Although, sudden weight loss is in itself an indication that something is not right with your bodys state of health so it is imperative that you visit your doctor for a check up. In the case of lymphoma patients, however, they found themselves losing ten or even fifteen pounds over just a couple of months without doing any exercises or changing their diet or eating habits at all.
Fever is also an indication of a possible lymphoma diagnosis especially if the fever comes and goes and is like that for a long time now. Fever often comes with body infections. People often mistook lymphomas as mere infections. Again, it is reiterated that consulting your doctors when you experience such fevers is highly recommended.
Other signs include excessive sweating at night which not only is quite unique to lymphoma but is also very uncomfortable which in a way signals the person to have his body checked. People who experience this abnormal sweating behavior wake up practically drenched even if they did not have any nightmares whatsoever or fell asleep in a room with extremely hot temperature. Just like excessive sweating, feeling itchy all over is another unique symptom of lymphoma. The itchiness comes from the release of chemicals from the cancer cells.
Fatigue and loss of appetite are also quite common in lymphoma patients. People actually feel this way because the cancer cells have grown considerably that they are practically sucking most of the nutrients you get from the food you eat. And with the loss of appetite the cancer cells sucks more of the bodys nutrients thats why it is only natural that you feel weak.
The good thing about medical science is that they continue to find ways of treating various ailments and diseases. Lymphoma can be treated and with early detection the treatments are more effective with more positive results. We just need to heed the lymphoma warning signs to help patients with lymphoma get an immediate diagnosis and treatment.
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Knowing Your Cancer, How Lymphoma Spreads
These are some facts according to the Leukemia & Lymphoma Society: 19.5 out of every 100,000 people in the world develop Non-Hodgkins Lymphoma while 2.8 out of every 100,000 people in the world are diagnosed with Hodgkins disease. Hodgkins disease and Non-Hodgkins Lymphoma are two of the main classifications of lymphoma, a cancer of the bodys lymph system. The lymph system, being part of our immune system, is tasked to eliminate bacteria, diseases and infection from our body. But when the cells multiply abnormally, tumors begin to appear in the lymph nodes. You can feel these as lumps in the nodes of the neck, armpit and groin. Soon the cancer cells will spread in other parts of the body, how lymphoma spreads is a good thing to know.
Metastasis. This is a word we often hear in cancer patients. This is actually a term which refers to the spreading of cancer to the rest of the body. Lymphoma at first is a single tumor in one of the many lymph nodes of the body. What happens when the cancer cells undergo metastasis is that cancer-infected cells break away from the main tumor and moves to another part of the body. The cancer cells use the bloodstream to move from one area of the body to another. The cancer cell can attach itself to another lymph node or to other organs of the body. When it fastened firmly, the cells reproduce again until it creates another mass of tissue to form as a tumor. Then the whole process repeats itself.
For lymphoma, the cancer cells use the lymphatic system of the body to spread. The lymphatic system of the body is pretty much like the bloodstream, it is spread although out the body since it is responsible for keeping the body clean from infections and diseases. The lymphatic system is an open canal where cancer cells can travel and create more tumors.
The tumors are pretty deadly. Because of the accelerated rate of growth, these cancer cells can continue to make the tumors grow. Soon enough the tumors grow large enough that the healthy tissues or organs are prevented to function normally. Eventually the healthy tissues or organs will stop functioning which spells death to the person.
Like any cancer, lymphoma has also a number of stages. These stages describe the severity of the condition and indicate how far the cancer cells have infected the body. Stage I is the first stage of the cancer. At this level, the cancer cells have only infected one lymph node or one part of the body. Because it is still developing, this stage is also referred to as the early disease.
The second stage or Stage II is far more alarming. At this point the cancer cells have metastasis and have infected another one or even more lymph nodes or parts of the body. However, at Stage II the infection is limited to either above or below the persons diaphragm. This stage is called locally advanced disease.
Stage III is known as the advanced disease. The cancer cells at this stage have found its way on both sides of the diaphragm and have established a number of tumors in those areas. The final stage or Stage IV or widespread disease is described by spread of the cancer cells to one or more of the bodys organs such as the bone, skin, liver or lungs.
This is how lymphoma spreads. That is why it is important for an early detection of the disease for proper and effective treatment.
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How Does One Get Lymphoma?
Lymphoma is a type of cancer that affects the bodys lymph system. Contrary to its name and to what some people might have told you, lymphoma is not just isolated on the lymph nodes and thymus gland for the lymph or lymphatic system is actually composed of the bone marrow, the thymus gland, the lymph nodes, tonsils, appendix and spleen. The system filters the waste or unwanted materials like fats and bacteria from the various body tissues. The one that picks up the bodys dirt is the lymph, a clear or sometimes yellowish fluid. But the question remains, how does one get lymphoma?
Unfortunately however, the answer to that question is not a simple one. For one, despite the thousands of hours spent on medical research and laboratory testing the actual cause of the disease is still an unknown. DNA mutation is one of the possible cause of why lymphoma develops but what happens why DNA have to mutate remains a big question to the medical science community. Medical scientists, nevertheless, have found several factors that can possibly increase the risks of developing lymphoma.
As you might have already guessed, the two general factors are genetic and environmental factors. Genetics for one is still a complicated issue that most likely cannot be resolved soon with a concluding answer. Inheriting the disease cannot still be ascertained as a valid cause. However, it was found out the people with inherited immune disorders are most likely to develop lymphoma as well. Immune disorders such as lupus, rheumatoid arthritis and celiac disease appear to have a hand in the development of lymphoma.
Likewise, those that have immune system disorders are also at a higher risk of developing lymphoma. Those that belong to this type of disorders include patients with HIV/AIDS, Helicobacter Pylori and Epstein-Barr virus (EBV). People with compromised immune systems like those with HIV/AIDS and EBV are often candidates for lymphoma as well.
On the environmental factors side, it should be common knowledge by now that various health hazards such as exposure to chemicals and radiation causes a variety of diseases, disorders or health conditions. And this includes developing lymphoma. More specifically, solvents like acetone, alcohol (yes various alcohols), xylene, turpentine, and benzene have found to associated with lymphoma.
The same can be said with chemical herbicides and pesticides which make farmers and various workers in the agricultural sector at a higher risk on developing the disease. Some hair dye products have also been found to be a significant factor to the development of lymphoma in some patients. Although, it seems that the hair dye products that shown such effects were those manufactured before the 1980s.
How does one get lymphoma? To fully answer that question means giving more time and more funding to the medical science community to do their research and testing. Lymphoma cases are not going down and definitely the disease is not something that can be eradicated in a quick span of time. But for now, we should at least try to avoid the various factors that increase our risk of contracting the disease. Prevention is still the best cure.
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